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Cambridge International AS & A Level Biology Revision

Explore Cambridge International AS & A Level Biology revision topics. This qualification is not a GCSE; the existing guide address and saved checklist are retained. Check the official specification for complete requirements.

Qualification code: 9700

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Course details

CIE · International A Level Biology9700Exam years · 2027

Assessment For assessment details, see the official specification.

Tick a point after revising it. Progress is saved on this device and does not measure mastery.

Reviewed course guidance

Revision points, with the explanation beside them

Open a point to read what to know, how to use it in an assessment, a plain-language explanation and a self-check. Answers stay hidden until you choose to reveal them.

Options and source

Cambridge International assessment route

  • AS only: Papers 1, 2, 3
  • Staged A level: AS Papers 1–3, then A level Papers 4–5
  • Linear A level: Papers 1–5 in one series

Syllabus overview: AS-only, staged and linear assessment routes

Topic group

Reviewed requirements

1 revision points
  • Core

    Scope: Core · 9700 §3.2 Factors that affect enzyme action, learning outcome 2: Vmax, Michaelis–Menten constant Km and comparison of enzyme affinity

    Open revision guidance

    What to know

    • On a Michaelis–Menten rate-versus-substrate-concentration curve, Vmax is the maximum rate approached at high substrate concentration. Km is the substrate concentration associated with half Vmax in the standard model. When conditions and model are comparable, a lower Km indicates greater apparent affinity between enzyme and substrate.

    What to do in an assessment

    • Read Vmax from the plateau and half that rate; locate the substrate concentration at that rate to estimate Km. Compare Km values only for comparable conditions and do not confuse Km with Vmax.

    In plain language

    Vmax is a rate; Km is a substrate concentration. The specification uses Km to compare enzyme affinity.

    Self-check

    At half of Vmax, enzyme A requires 2 mmol dm⁻³ substrate and enzyme B requires 5 mmol dm⁻³. Which has the lower Km and greater apparent affinity?

    Show the answer

    A has the lower Km (2 mmol dm⁻³) and therefore the greater apparent affinity under comparable conditions.

Earlier topic checklist

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Biology topic list

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These ticks keep your earlier topic checklist. They do not count towards the new reviewed requirements above. Its numbering may be internal; use the linked references above for the exact reviewed source requirements.

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